Conduct HPLC purity assessment of samples and troubleshoot analytical data for purity confirmation using various chromatographic techniques.Carry out preparatory HPLC purification of crude reaction mixtures.Support organic reaction monitoring by LC-MS.Maintain PM and calibration service records of instruments.Perform primary instrument troubleshooting.Requires excellent time management with the ability to manage projects on time.Work collaboratively with the chemistry team,the biology team and laboratory staff to conduct project activities and resource usage.Maintain a clean laboratory work area and exhibit safety awareness.Follow responsible actions regarding chemical handling and disposal.Participate in project team meetings.Preferred candidate profile
- Ph.D. / M.Sc / M.Pharm Analytical Chemistry / Biochemistry (or a related discipline) with 2 to 5 years of experience in Drug Discovery or Chemical CRO
- Deep expertise in preparatory HPLC and Mass spectrometry
- Essential to have a deep understanding of column chemistries and HPLC detection methods
- Must possess a thorough understanding of analytical technologies used for chemical characterization
- Exposure to in-vitro ADME testing is a strong plus
Skills Required
Purification, peptides, characterization, Lcms, Hplc