Upstream Manufacturing

Date : 24 Sept 2025

Location :

Bangalore, KA, IN, 560099

Custom Field 1 : Manufacturing Services

Job Title : Upstream Manufacturing

Job Location : Bangalore

About Syngene : Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit

Role-specific

• Follow good aseptic behaviour inside Biologics operations facility.
• Perform all the upstream activities like Assembly preparation, Media Preparation, Vial thaw, Feed preparation and filtration, Bioreactor Operations to Batch Harvest.
• Monitoring and process control of the specific Operations of the upstream.
• Maintenance of Quality records.
• Traceability from raw material till finished product.
• In-process product sampling and storage.
• Preparation and review of operation related documents.
• Perform room owner responsibility for the assigned USP area.
• Perform equipment / instrument ownership related responsibilities related to USP.
• Initiate Complaint Slips (work orders) for USP related areas and equipment.
• Coordinate with QA for line clearance.
• LNS system monitoring and LN2 tank refilling.
• Gas Bank Monitoring.
• Maintaining process area All-time ready for Inspection / audit purpose.
• Preparation of general upstream related procedures, protocols, risk assessment and BMRs.
• Execution of protocols related to upstream related activity and equipment / instrument qualification.
• General consumable stock review and record maintenance
• Ensure PM planner and calibration planner are followed.
• Execution of batch activity as per BMR and report nonconformity to the supervisor.
• Issuance of annexures, RM, consumables and BMRs.
• Tracking of work order status and ensuring timely closure.
• Involve in downstream related activities under supervision of downstream supervisor.

Education And Experience

Education

Master's degree / bachelor's degree in pharmacy, Master's degree in Pharmaceutical Sciences.

Industry Experience

Other Competencies Required For The Role

Safety And DI Responsibilities

Equal Opportunity Employer

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and / or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

Pls visit us at https : / / syngeneintl.com / to know more about us and what we do.

Skills Required

Filtration, Media Preparation