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Research Associate / Senior Research Associate - Synthesis
ConfidentialAhmedabad8 days ago
Job descriptionEducation : M.Sc. (Organic Chemistry) or M. Pharm (Pharmaceutical Chemistry) Experience : 2 to 6 years in a synthetic chemistry or process R&D role, preferably in an API pharma company Strong knowledge of organic reaction mechanisms and modern synthetic techniques. Proficiency in lab equipment and handling air / moisture-sensitive reactions (if applicable). Experience in scale-up considerations and working in kilo-lab / pilot plant (preferred). Familiarity with regulatory guidelines (ICH, cGMP, etc.).
Key Responsibilities :
- Design and execute multi-step organic synthesis for APIs and intermediates at lab scale.
- Conduct literature searches (SciFinder, Reaxys, etc.) to plan synthetic routes and understand prior art.
- Develop and optimize synthetic methodologies with a focus on scalability, cost-effectiveness, and safety.
- Perform purification techniques (crystallization, chromatography, distillation, etc.).
- Analyze reaction intermediates and final products using analytical tools such as NMR, HPLC, GC, LC-MS, FTIR, etc.
- Maintain detailed documentation of experimental procedures, observations, and data in lab notebooks and reports as per GLP / GMP guidelines.
- Collaborate with Analytical R&D, Process Development, and Scale-Up teams to ensure smooth technology transfer.
- Adhere strictly to safety protocols and environmental guidelines during lab operations.
- Contribute to troubleshooting and problem-solving efforts during route development and scale-up.
- Support patent writing and intellectual property documentation where applicable.
Required Qualifications :
Key Skills and Competencies :
Skills Required
Organic Synthesis, Analytical Techniques, literature review, Data Analysis
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Research Associate • Ahmedabad