Deputy General Manager (DGM) / Assistant General Manager (AGM) – Upstream Production (API)

Key Responsibilities :

Production & Operations Management :

Manage end-to-end

upstream processes

including

chemical reactions ,

crystallization ,

solvent recovery , and

work-up operations .

Plan and execute daily production activities to meet

output, quality, and yield

targets.

Monitor

critical process parameters (CPPs)

and ensure adherence to process design and safety.

Compliance & Documentation :

Ensure

GMP compliance , and adherence to

regulatory

and

safety guidelines

(USFDA, EDQM, TGA, WHO).

Review and approve

Batch Manufacturing Records (BMRs) ,

SOPs ,

Deviation Reports , and

Change Controls

related to upstream activities.

Prepare and support

regulatory audits ,

customer audits , and

internal inspections .

People & Resource Management :

Lead and develop a team of

shift engineers, supervisors, and operators .

Schedule manpower, oversee training and ensure adherence to

SOPs and safety practices .

Foster a culture of

accountability ,

teamwork , and

continuous improvement .

Process & Quality Improvement :

Collaborate with

R&D, Technology Transfer, and QA / QC

teams to ensure smooth

tech transfer

and

scale-up

of new products.

Drive

process optimization

to improve

yield, reduce cycle time , and

minimize solvent loss .

Lead

investigation of deviations, process failures , and implement

corrective actions .

Plant & Equipment Oversight :

Oversee the operation and maintenance of key upstream equipment :

Reactors (GLR / SSR), condensers, scrubbers, distillation units, receivers , etc.

Coordinate with the Engineering team for

preventive maintenance

and

equipment validation .

Inventory & Cost Control :

Monitor raw material consumption, solvent usage, and utility consumption.

Drive

cost-reduction initiatives

without compromising quality or compliance.

Key Skills and Competencies :

Deep understanding of

chemical reaction engineering

and

process safety .

Expertise in

hazardous reaction handling , including exothermic and pressure reactions.

Sound knowledge of

GMP ,

cGMP ,

ICH , and

regulatory requirements .

Strong leadership, team management, and problem-solving abilities.

Proficiency in production software (e.g., SAP, DCS, MES) is an added advantage.

Educational Qualifications :

B.E. / B.Tech

in

Chemical Engineering

or equivalent OR

M.Sc. in Chemistry / Organic Chemistry / Industrial Chemistry

Experience Required :

15+ years of progressive experience in

API manufacturing , with significant expertise in

upstream operations

including

reaction handling ,

crystallization , and

phase separation .