Senior Infrastructure Systems Engineer

Position Overview :

Guardant Health is seeking a Senior Infrastructure Systems Engineer to develop, manage and support our enterprise virtualization and Linux infrastructure. This role focuses on VMware, Linux systems, enterprise storage, and automation, playing a key part in delivering reliable and scalable platforms for mission-critical operations.

Key Responsibilities :

• Design, configure, and support Linux systems (RHEL, Oracle Linux, Ubuntu) on virtual and physical platforms.
• Manage filesystems, LVM, partitions, mount points, and performance tuning.
• Perform OS patching with Red Hat Satellite, Ubuntu Landscape, or similar tools.
• Automate tasks using Ansible, Terraform, Bash, or Python.
• Implement / maintain authentication / identity configurations using Kerberos and SSSD.
• Troubleshoot complex OS, storage, and networking issues.
• Architect and operate VMware infrastructure (vSphere, ESXi, vCenter, vSAN, NSX).
• Manage Horizon VDI pools, connection servers, and end-user experience.
• Integrate and optimize PURE Storage for VMware workloads.
• Administer backup and recovery using Rubrik and Pure Storage snapshots.
• Monitor infrastructure health and plan for capacity and DR readiness.
• Support hybrid workloads in AWS, including EC2 and storage services.
• Work with container platforms such as Docker and Kubernetes.

Qualifications :

Preferred Qualifications

Why Join Us :

At Guardant Health, you'll help build and support infrastructure that powers cutting-edge cancer diagnostics. You’ll work with modern technologies, collaborate with global teams, and contribute directly to projects that make a difference in patient care. This is your opportunity to grow your expertise while supporting a mission that matters