Structural BiologistMeril • Alwar, IN
Structural Biologist
Meril • Alwar, IN
18 hours ago
Job descriptionAnalyze protein-ligand interactions to inform medicinal chemistry and lead Conduct molecular dynamics (MD) simulations and free energy calculations to Apply structural insights to guide hit-to-lead and lead optimization strategies. (Preferred) Utilize machine learning models to support binding site prediction or Strong expertise in structural biology techniques, such as crystallography, cryo- Proficient in macromolecular modeling and structure refinement tools (e.g., Experience with protein-ligand docking, structure validation, and interaction Hands-on experience with molecular dynamics simulations using tools such as Familiarity with structure-based drug design platforms (e.g., Schrödinger, Scripting or programming experience (Python, R, Bash) for workflow automation and Ph.D. in Structural Biology, Biophysics, Computational Biology or related field. Demonstrated experience in drug discovery pipelines, especially in target (Preferred) Background in machine learning or AI applied to biomolecular structure Strong publication record or demonstrated project impact in therapeutic Work on high-impact, discovery-stage therapeutic programs. Collaborative and interdisciplinary research environment. Access to state-of-the-art computational and structural biology platforms.
Job Description :
- We are seeking a highly skilled and motivated Structural Biologist to join our drug
discovery programs. The ideal candidate will bring deep expertise in
macromolecular structure determination and modeling, with a focus on elucidating
protein structures, analyzing ligand binding, and driving rational drug design in
collaboration with computational and medicinal chemistry teams.
Key Responsibilities :
optimization efforts.
evaluate complex stability and binding energetics.
compound prioritization.
Required Skills & Experience :
EM, or NMR are desirable.
Phenix, Coot, Chimera, PyMOL).
mapping.
GROMACS, AMBER, NAMD, or CHARMM.
AutoDock).
structural data analysis.
Preferred Qualifications :
validation and lead optimization.
or ligand interaction prediction.
development.
What We Offer :
Create a job alert for this search
Structural • Alwar, IN