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Manager / sr. manager - downstream processing, r&d
Panacea BiotecDelhi, Delhi, India5 days ago
Job descriptionPurification method development, optimization, & execution for bacterial & viral vaccines. Experience in Cell lysis, different chromatography platform, TFF system, Filtration unit and other unit operations used in protein purification. Purification method optimization and development for protein expressing in E.coli and mammalian cell culture. Execution of In –House Calibration of AKTA System, spectrophotometer, Auto pipettes, Weighing balance and supervision of In –House Calibration of p H / conductivity meter. Execution of scale up & scale down experiment for purification of Vaccines and biologics to obtain high yield & quality product. Downstream Process development, optimization & scale up of different vaccine bulk (Dengue Vaccine, Hepatitis A Vaccine and E.coli, BPBC / CEPI Vaccine). Co-ordination with technology
Best fit profile
- Knowledge in handling and troubleshooting purification methods at small scale and pilot scale
- Various Chromatography techniques like Ion exchange, Affinity, HIC etc.
- Ultrafiltration – TFF (Hollow Fiber / Cassettes).
- Should be well versed with FPLC, AKTA- Process, AKTA- Pilot.
Responsibilities
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Sr Manager • Delhi, Delhi, India