Key Responsibilities :
- Perform aseptic handling for various upstream operations.
- Prepare media and feeds for shake flask experiments and bioreactor batches.
- Handle shake flasks for clone selection, media optimization, and feed strategy development.
- Prepare and maintain bioreactors at different scales (1L, 5L, 20L).
- Execute upstream batches in small-scale and large-scale bioreactors.
- Conduct in-process sample analysis including cell count, viability, and metabolite levels (glucose, lactate, ammonia, glutamine, etc.).
- Draft and maintain Standard Operating Procedures (SOPs) for instruments and processes.
- Participate in shift duties for continuous batch monitoring and process support.
- Collaborate effectively within a team environment to ensure smooth upstream operations.
Skills Required
mass spectrometry, protein characterization, Troubleshooting