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Manufacturing Associate - Downstream
Manufacturing Associate - Downstreammicro crispr pvt. ltd. • Vapi, India
Manufacturing Associate - Downstream

Manufacturing Associate - Downstream

micro crispr pvt. ltd. • Vapi, India
30+ days ago
Job description

Job Title Options (Choose One)

Executive / Sr. Executive – Downstream Process ( Biologics)

(Avoid 'Production Executive.' Too small for the gravity of this work.)

About the Role

Join a team shaping the future of advanced therapeutics, where every purification step brings life-changing treatments closer to patients.

As part of the Manufacturing team, you will support downstream processing of viral vectors and biologics — ensuring purity, consistency, and compliance within a GMP-regulated environment.

This role is ideal for professionals who enjoy translating process science into scalable manufacturing reality.

Key Responsibilities

  • Execute downstream manufacturing activities including filtration, chromatography, and bulk formulation under GMP conditions.
  • Prepare buffers, solutions, and process materials as per approved batch records.
  • Operate and maintain downstream equipment such as TFF systems, AKTA chromatography skids, depth filters, and associated single-use technologies.
  • Monitor critical process parameters and document activities in real time following GDP practices.
  • Support technology transfer and process scale-up activities.
  • Troubleshoot process deviations and assist in investigations.
  • Work closely with Upstream, QA, QC, and Validation teams to ensure smooth batch execution.
  • Maintain strict adherence to aseptic practices, safety guidelines, and contamination control strategies.

Ideal Candidate Profile

  • 1–5 years of experience in downstream processing within biologics, vaccines, biosimilars, monoclonal antibodies or viral vector.
  • Hands-on exposure to purification techniques such as:

Chromatography

Tangential Flow Filtration (TFF)

Ultrafiltration/Diafiltration

Depth filtration

  • Familiarity with GMP documentation and manufacturing workflows.
  • Strong problem-solving mindset with high attention to detail.
  • Comfortable working in cleanroom environments.

Education

  • M.Sc / B.Sc in Biotechnology, Microbiology, Biochemistry
  • B.Tech / M.Tech in Biotechnology or Bioprocess
  • M.Pharm (Biotech)


Skills Required
depth filtration , Chromatography, ultrafiltration
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Manufacturing Associate - Downstream • Vapi, India

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