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Research Scientist / Team Leader – Biocatalysis, Protein purification & Downstream (15h Left)

Research Scientist / Team Leader – Biocatalysis, Protein purification & Downstream (15h Left)

PI Industries LtdIndia
2 days ago
Job description

Key Responsibilities :

  • Design and execute experiments for enzyme screening, expression, and purification (affinity, ion exchange, HIC, SEC, etc.).
  • Design studies and lead workstreams for lab‑to‑kilo scale (biotransformations 0.1–20 L; purification mg–10 g and higher)
  • Drive process robustness / scale‑up, troubleshoot enzyme stability / mass transfer / fouling / resin lifetime.
  • Characterize enzymes using biochemical and biophysical techniques (SDS-PAGE, HPLC, LC-MS, UV-Vis, etc.).
  • Collaborate with molecular biology, fermentation, and analytical teams to ensure seamless workflow.
  • Maintain accurate records, analyse data, and present findings in internal meetings.
  • For TL / SRS roles : Lead project teams, coordinate cross-functional activities, and contribute to strategic planning.

What You Bring :

Qualification : M.Sc. / M.Tech. / Ph.D. (Ph.D. is preferred for SRS / TL) in Biochemistry, Biotechnology, Chemical / Bioprocess Engineering with excellent academic credentials, and peer-reviewed papers / patents

Experience :

  • RS : 3–5 yrs. (M.Sc.) or fresh Ph.D.
  • SRS : 5–8 yrs. (M.Sc.) or 2–4 yrs. (Ph.D.)
  • TL : 8–12 yrs. (M.Sc.) or 5–8 yrs. (Ph.D.) with ≥2 yrs. team leadership.
  • Biocatalysis : Enzyme selection / screening, cofactor recycling, immobilization basics, solvent / aqueous systems, pH / DO / mass transfer control, scale‑up, green metrics
  • Purification / Downstream (from industry) : Clarification, precipitation, AKTA / FPLC, chromatography (Affinity / IEX / HIC / SEC), UF / DF / TFF, solvent exchange, crystallization / lyophilization.
  • Analytics / Tools : HPLC / UPLC, GC, LC‑MS, SDS‑PAGE, chiral analytics, DoE (JMP / Minitab), ELN / LIMS, strong Excel / data handling.
  • Functional Competencies : Scientific knowledge, Experimental skills, Documentation, Data reporting, analysis and interpretation

    Behavioural Competencies : Drive for result, Clear communication, Safety / process adherence, Ability to work independently and in a team-oriented environment.

    Interested Candidates are requested to share their resumes on shubhi.chandnani@piind.com

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