Overall Role:
Support in-house sample analysis, functional characterization and assay development activities.
Perform routine sample analysis supporting comparability and formulation robustness studies, participate in cell-based assay development, optimization, and qualification.
Education & Experience Requirements:
- BS or MS degree in a relevant scientific discipline (please no Phd candidates)
- +Minimum 3 years experience
Essential Duties:
- Perform cell-based reporter assay and flow cytometry analysis to support late-stage biologics projects.
- Plan and execute assigned experiments that support assay development activities and project goals.
- Proactively seek out senior personnel to discuss potential solutions to problems.
- Participate in group meetings to share test results.
- Demonstrate ability to recognize anomalous and inconsistent results and interpret experimental outcomes.
- Develop skills in data analysis and ability to evaluate quality of data.
- Operate scientific equipment, selects appropriate methods and techniques to perform experiments, and prepare related reports.
- Plan and organize details of experiments with guidance.
- Basic understanding of cell-based methods.
- Experience with cell-based assays and flow cytometry analysis and perform routine maintenance of these instruments.
- Develop flow cytometry, flow imaging assays, and explore new technologies and methodology for viral vector characterization and help develop a robust process for vector production.
- Responsible for data analysis using Softmax pro software and graphic display of data using Excel and Power Point presentation formats.
- Demonstrate good verbal communication skills and interpersonal skills to provide insight into the processes used to achieve results of assigned tasks.
- Be able to work in a fast-paced and highly collaborative working environment.
Must have requirements/skills:
- Experience with performing cell culture ? Experience working with biologics (proteins, fusion proteins, mAbs)
- Experience with analytical methods such as ELISA, cell binding assay, or reporter assay
Nice to Have Requirements/Skills:
- Experience working with antibody drug conjugate (ADC)
- Experience working with pseudovirus generation or virus neutralization assay
- Good presentation and documentation (electronic note book-ELN, testing methods, etc.)