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Senior Scientist- DMPK ((Large molecule / ADC PK and bioanalysis, ADC characterisation and bioanalysis

Senior Scientist- DMPK ((Large molecule / ADC PK and bioanalysis, ADC characterisation and bioanalysis

Aurigene Oncology LimitedBengaluru, Karnataka, India
9 days ago
Job description

Desired Profile : M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 12-15 years or Ph.D. with 5 years’ experienceJob Description, Key Skills and Competencies : - Expert in designing and executing DMPK studies to support antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs, from discovery through IND-enabling stages.- Extensive experience in quantification of biologics including antibodies, therapeutic proteins, ADCs, and peptides using LC-MS / MS, MSD, and ELISA platforms.- Proficient in advanced bioinformatics tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software.- Skilled in applying innovative techniques for function-based identification and selection of ADC and mAb lead candidates, with a strong focus on DMPK profiling to ensure safe and effective therapeutic development.- Experienced in interpreting complex DMPK data and providing actionable insights to cross-functional project teams.- Actively represent DMPK functions in internal and external meetings, fostering collaboration and strategic alignment.- Collaborate closely with cross-functional departments to address ADC-related challenges and deliver integrated solutions from target validation to IND submission.- Accountable for authoring and reviewing SOPs, study protocols, reports, and regulatory documentation to support both GLP and non-GLP studies.- Strong foundational knowledge of DMPK principles, including PK / PD, toxicology, and translational sciences. Demonstrated capabilities in communication, innovation, and team leadership.Competencies : - Antibody, ADC characterisation- Communication Skills- Excel software Skills- Interpersonal Skills

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Senior Scientist • Bengaluru, Karnataka, India