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Senior Scientist - ADC Medicinal Chemistry

Senior Scientist - ADC Medicinal Chemistry

Aurigene Oncology LimitedTirupati, IN
19 days ago
Job description

Desired Profile :

  • PhD (Organic chemistry / Medicinal chemistry) with 5 -6 years of experience in Antibody Drug Conjugates (ADC) development

Roles & Responsibilities :

  • Must have hands on experience in linker- payload synthesis and overall understanding of ADC.
  • Should be able to design and execute synthesis of complex drug linkers and ADC payloads.
  • Should have proficiency in characterization and analysis of synthesized molecules using analytical techniques such as HPLC, LC-MS and NMR.
  • Thorough understanding of linker chemistry and latest development in the space.
  • Efficient employment of structure-based drug design principles and integrate with other experimental data collected in the design of new linkers.
  • Mentor and manage team members for high performance and scientific growth.
  • Collaborate with project team members and communicate progress against goals in a multidisciplinary setting : chemistry, antibody engineering, biology, pharmacology, DMPK, and external collaborators.
  • Accurate documentation of experiment and maintaining a well-organized laboratory notebook (LNB).
  • Understanding of systems and process related to safety, health, and environment (SHE).
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