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Scientist - Research & Development (Downstream Process Development)

Scientist - Research & Development (Downstream Process Development)

Immuneel Therapeutics Pvt. Ltd.Bengaluru, Karnataka, India
2 days ago
Job description

About Immuneel

Immuneel Therapeutics Private Limited is a pioneering start-up company leading the charge in cell therapy and personalized immunotherapy for patients in India. For more details, please refer www.immuneel.com

We Pursue, with Purpose, to serve our Patients (3 Ps) by Connecting within, Collaborating globally and Creating (3 Cs) solutions. Our flexible, diverse, and vibrant team is bringing together best practices and innovations in the field of cell and gene therapy.

Working at Immuneel promises the excitement of an agile startup on a critical mission. Proudly Indian in solutioning, yet global in outlook, we are keen to collaborate. We value diversity including in experience and perspectives. We value work-life balance and believe that having fun on the job is integral to achieving the right results. We pride ourselves on providing an open environment and our mission resonates with humanity everywhere. At Work, we are :

  • Passionate in driving patient outcomes : We are passionately committed to doing the RIGHT thing to achieve the best outcomes for our patients through innovation, agility and performance orientation. We put the impact on the patient above all else.
  • Responsible and accountable : We demonstrate ownership and accountability for our actions. We make timely and well-informed decisions, learning from our performance.
  • Transparent, honest, and supportive in how we work together : We insist on integrity and respect for the individual. We demand excellence. Our performance management is focused on excellence through timely and constructive feed-forward.
  • Inclusive and flexible : We are full of life and embrace all opportunities to collaborate and work together. We are excited about the collective knowledge and expertise that we share. “Being and thinking different” is valued.

Immuneel prides itself as an organization that is keeping pace with best practices in organization design. Our role-based organization incorporates global trends in human capital that promote focus on work and greater nimbleness. Our role-based structure allows you to be cherished by the work you do and bring value to your work rather than designations, our organization is simplified into a flat, non-hierarchical, millennial, organization where you may fully inherit the role you play in the organization and are recognized by the accountability you take and the work you deliver.

Immuneel’s employees are integral to our quest to develop and deliver high quality engineered cell therapies in India. We believe that our culture provides an environment for employees to excel and find purpose. The strength of our team is every bit as important as our cutting-edge technology and we invest in clear compensation and comprehensive benefits for our employees. People for us, are not resources, but our capital.

If you are a talented professional, an out-of-box thinker with a zeal to help change, and passionate about healthcare, we invite you to join us and be a part of a historic initiative in India.

Interested in being a part of the next revolution in cancer treatment? Send your resume to careers@immuneel.com

1. Role Title :

Scientist - Research & Development (Downstream Process Development)

2. Department / Function :

Research and Development

3. Reporting Structure :

  • Reports to : Viral Vector
  • Direct Reports : NA
  • 4. Role Summary :

    Immuneel is looking for an Engineer / Scientist with experience in downstream process development for viral vectors. The said candidate must have a strong understanding of various downstream processes like chromatography, tangential flow filtration and normal flow filtration. Key deliverables will be to drive projects and programs through process development culminating in global IND applications. Knowledge of analytical method development, single use technologies and process automation is an added advantage.

    5. Key Responsibilities :

  • Experimental design and execution for downstream process development for viral vectors, small molecules and cell therapy products.
  • Preparation, cross-functional review and training of MDRs, MTRs, MTPs and MQRs. Draft XOPs and other documents required for quality management system requirement.
  • Compilation and recording of data in Lab Notebooks (paper based and digital) and preparation of plans and reports. Coordination with Application Scientists and Engineers for technical trouble shooting Process Development facilities and associated utilities.
  • Resource management : ordering of reagents, consumables & inventory management.
  • Support process development in the form of routine cell culture and associated experiments.
  • Maintenance of laboratory equipment and instruments.
  • 6. Primary Objectives : Outline the key objectives the role is expected to achieve. These should align with the company’s goals and strategic priorities.

  • Downstream process development for viral vectors
  • Technology transfer of downstream process as a part of technology transfer of the viral vector manufacturing process
  • Associated documentation
  • Enable MSAT function by leading experiments for ongoing programs and / or in-licensed programs
  • 7. Competencies Required :

  • Technical Competencies :
  • Downstream process development
  • Bioprocess technology
  • Filtration inclusive of depth filtration and tangential flow filtration
  • Chromatography including ion exchange chromatography
  • Sterile filtration and fill-finish
  • Developed downstream process for viral vectors and / or mAbs
  • Understanding of CQA and CPP, Process Verification and Validation
  • CMC documentation experience
  • Soft Skills :
  • Project planning
  • Resource management
  • Data presentation
  • Budget preparation
  • Collaboration
  • Team Player
  • Willingness to Learn
  • Challenge
  • 8. Qualifications :

  • M.Tech. or PhD (Engineering / Science) with 2-5 years of industry experience in biologics / viral vector process development
  • 9. Working Conditions :

  • Role Type : Full Time and Onsite
  • Work Hours : 9 : 00 AM to 6 : 00 PM for the General Shift and 2 : 00 PM to 11 : 00 PM for the Post-Noon Shift (on a rotational basis). There will be two days off each week, which may not necessarily fall on a Saturday or Sunday.
  • Travel Requirements : Depends
  • Base Location : Immuneel Therapeutics Private Limited, 8th Floor, Mazumdar Shaw Medical Center, Narayana Health City, Bommasandra Industrial Area, Bangalore - 560099
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